About pressing of tablets

• The answer to the questionHow to properly mix the powders to mix?Mixing of powders, especially in unequal proportions, the process is very complicated. Visually determine the quality of mixing powder impossible. Buy any powder mixer you should know some of the secrets of mixing powders from our website.

1. Equal-sized particles dismount better. If you need to mix some powder in a mixture of the best way to pre-grind them up to the same faction. Fraction of the size of the powder particles. For example uniformly mix the sugar crystals and powder will be difficult, and if crushed crystals, the mixing quality will be higher.
2. In the mixed powder plays an important role in the percentage of each powder mixture. If you have a problem to mix 9 kg per 1 kg of powder and a second, I recommend to stick to rules 50-50. Ie you load into your blender (powder mixer) 1 kg powder first and second 1 kg. Mixing two equal parts powders give good result interpenetration and you get a uniform mixture tablet weighing 2 kg. Adhering to the rules of 50x50, you can already 2 kg tablet blend load 2 kg of powder, which was 9 kg. Typically 50 to 50 time-tested on different types of mixers.
3. Typically, there is a situation where one substance (the active drug component) in a mixture of 1-10% of the tablet, and 90-99% filler. We strongly recommend that you have 2 pieces of mixers. The first mixer for mixing micro-portions. For example you need to make a mixture of 100 grams or 500 grams to subsequently bring this portion to 20-30 kg. Use the mixer 2. The first maximum load capacity up to 3.5 kg of powder, and the second is 20 or more pounds of powder. If you have a mixer powder only on big volume, then micro-portions of the tablet will be impossible to stir the mixture (without difficult and quality assurance).
4. Frequently the powders are oily substances existing structure. If this powder is placed between your fingers and rub, then felt the effect of "fat." Such powders entering the mixer just slipping into a ball and in no way apply to the rest of the powder mass. Recommend the following course of action. Using corn starch, white premium. In the oven is heating up to 30-50 degrees starch, dried of all moisture. Then triturated its "waxy" starch, thereby your powder nalipnet for starch and you get what that ability to mix this powder in the future with other fillers.
5. There are many models of mixers powders. There contactless wherein rotating the tank and the powder within the inverted and thereby the mixing. This type of mixer is suitable only for well-flowing powders. If you like to download a mixer powder with "bold" effect, you get a snowball. Ie powder into a ball knock, and the current distribution of the powder in bulk get. I recommend that you always contact the powder mixers, where the blades that break up clots than powder and stir in a uniform mass. Contact mixers powders can be used to moisten the powder granulating.

To all the questions related with production of tablets you can find answers on resource www.Tabletpress.ru