Coating of tablets
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Theoretical materials on the website www.Tabletpress.ru
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Coating of pellets, granules and tablets.
Application methods and equipment
At the end of tabletting process often necessary coating of ready tablet. Meaning of coating tablets in pharmaceutical industry more and more increases. In the modern industry high-quality coverage is the major factor of stringent requirements to reliable and high performance coating technology.
Multilateral meaningof coated tablets has goals such as protection from adverse external influences (oxygen and carbon dioxide of air, light and moisture) content of tablets;
Improving the color and taste of the drug (hiding the objectionable odor and taste); localization of therapeutic effects of drugs in the stipulated department of gastrointestinal tract;
Prolongation of therapeutic effect of drugs in tablets; protection from the acidic environment of gastric juice medicinal substances contained in tablets; protection the mucos of stomach, esophagus and mouth from irritating effects of drugs; overcoming multi-directional (incompatibility) of different substances in one tablet by method of insertion coating and tablet-core in their composition;
Improving the appearance of tablets (coloring, gloss, leveling the surface roughness) and convenience of use.
Shells meet the following requirements: coating must be chemically indifferent (i.e. should not have negative effect on an organism) and be remoded from human organism naturally.
In the modern pharmaceutical industry, there are several types of coating: film, pelleted (or sugar-coated), multi-layered and pressed (or dry).
Application methods and equipment
At the end of tabletting process often necessary coating of ready tablet. Meaning of coating tablets in pharmaceutical industry more and more increases. In the modern industry high-quality coverage is the major factor of stringent requirements to reliable and high performance coating technology.
Multilateral meaningof coated tablets has goals such as protection from adverse external influences (oxygen and carbon dioxide of air, light and moisture) content of tablets;
Improving the color and taste of the drug (hiding the objectionable odor and taste); localization of therapeutic effects of drugs in the stipulated department of gastrointestinal tract;
Prolongation of therapeutic effect of drugs in tablets; protection from the acidic environment of gastric juice medicinal substances contained in tablets; protection the mucos of stomach, esophagus and mouth from irritating effects of drugs; overcoming multi-directional (incompatibility) of different substances in one tablet by method of insertion coating and tablet-core in their composition;
Improving the appearance of tablets (coloring, gloss, leveling the surface roughness) and convenience of use.
Shells meet the following requirements: coating must be chemically indifferent (i.e. should not have negative effect on an organism) and be remoded from human organism naturally.
In the modern pharmaceutical industry, there are several types of coating: film, pelleted (or sugar-coated), multi-layered and pressed (or dry).
Questions about tablets
To all the questions related with production of tablets you can find answers on resource www.Tabletpress.ru
- How to mix powders correctly?Mixing of of powders, especially in unequal proportions, is very complicated process. It is impossible to identify the quality of mixing powder visually. When buying any powder mixer you should know some secrets of mixing powders from our website.
- How to granulate powders?Granules. Pharmaceutical granulation of powders, granules, as the final form of product or intermediate state of powder which improves flowability at pressing tablets. Learn more details from us.
- How to press powders?Many customers do not envisage the technology of powder pressing, for all that the powder should be uniform in composition, free-flowing well, with the minimum allowable humidity. Which factors influence positively, and which make it difficult to press tablets read on our site.
- How to cover a tablet?Pelleting of tablets - covering the tablet surface with protective and decorative coating. Select the shell material, study the technology of panning tablets and principles of Dragee pans.
- How to remove dust from tablets?In the process of compressing tablets at them, as well as on the working surfaces of the press formes a layer of powder. Further, when this layer of dust is not removed from tablets, it leads to malfunction of counting and filling machines, dusty tablet hinders coating solid shell. We share with you, what means to remove dust, dedust tablets.
- How to count and prepack tablets?After pressing, there is a question about packaging of tablets in container. Wherever necessary accurate counting of ready tablets, required precision counting machines for packing tablets. Read the review of such equipment.
- How to distinguish tablets from briquettes?Square tablets, oval tablets, circular tablets, tablets from salt, coal tablets, tablets with logotype, tablets for washing machines - which are tablets and which are briquettes already. Dimensions and shapes of tablets.
- How to pack tablets in blister?The most popular type of packaging of tablets - Blister contour cellular package. Blister packaging for tablets is PVC film and a layer of heat-sealing aluminum foil. Under high temperature are formed cells of desired shape, after filling, the top is sealed with aluminum foil.