About pressing of tablets

• The answer to the questionAs pressed powders?Many customers do not represent the technology of powder pressing, but meanwhile the powder should be uniform in composition, good bulk, with minimum allowable humidity. What factors influence positively, and which impede pressing tablets we read.

1. You can compress any powder, it is important to choose the best technology and the press. Each case is a compromise between the need to finalize the tablet mass or purchase more powerful and expensive press. Recommend starting as follows. Decide on the size, shape and thickness of the tablets that are going to be pressed. Prepare your powder to the final stage, ie Mix all the powders into a single tablet mass composition. Test the hand to hand powder run, scoop in your fist powder and squeeze as much as possible. Open hand, if the powder was in the form of print and a small amount of powder crumbled, then you can buy the smallest effort on press. If the powder broke into several large pieces, and the percentage of fine powder in the palm visually no more than 50%, then your need to compress the powder with the press with maximum force, including those that you can find. And the last option, if the powder after uncompressing fingers remained in the initial state of loose powder, then you need to start working on domeshivaniyu in the binders, sealants additives. Then again, perform the test hand.
2. Some customers easier, but more expensive to buy the most powerful model of the press. Others customers want to save money on equipment and technology involved in the preparation of the powder. In any case, my advice - pre-screening and subsequent powder (if required) training. Maximum load on the pressing force should not exceed 70% of the specifications of the index. Additives to improve powder compaction are articles on this site.
3. The next problem which usually occurs when using tablet presses - poor flowability of the powder. If your powder has a fine fraction, such as the similarity of flour, and visually in this powder a lot of air, such a powder will just hang in the hopper of the tablet press. Thereby preventing the ingress of uniform doses matrix. There are two solutions - the addition of a fine powder supplements in the form of larger crystals that provide movement of the powder in the hopper, the second is the solution - your powder granulation, the choice of - dry or wet you define based on the composition of your powder. After the granular powder gives a more uniform in weight and quality of the tablet.
4. Powder sticking to the punches and the inner walls of dies. It takes many unpleasant tendency manufacture of tablets. The decision can be read - drying powder (check the moisture level of your pellets or feedstock). If necessary, drain. It can also affect active factor and humidity. The most excellent way to deal with sticking to punches are powders of calcium stearate and magnesium stearate. With their addition of any problem with powder sticking out. Add gradually to the minimum necessary dose to onset of effect. Some get 0.5% by weight. There are cases and use 5% stearate. In any case, mixing powders need to understand that what it will effect a certain powder buildup and in preparation mixture is taken into account. Also helps polish punches.
5. Some powders have high abrasive properties as well and to destroy the aggressive action. Conventional models are tablet presses with standard molds. Recommend everyone to handle all parts in contact with the powder reinforcing structures. There are a variety of electro-chemical methods for hardening steels. This will increase the life of the tablet press several times.

To all the questions related with production of tablets you can find answers on resource www.Tabletpress.ru